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ea0077oc6.5 | Thyroid | SFEBES2021

Effects of in utero thyroid hormone exposure on human neurodevelopment: MRI analysis from the Controlled Antenatal Thyroid Screening Study

Scholz Anna , Bloomfield Laura , Chambers Mari , Bhargava Raghav , Taylor Peter , Ludgate Marion , Lazarus John H , Jones Derek , Rees Aled

Background: The Controlled Antenatal Thyroid Screening II (CATS) study, a large randomised trial of thyroxine supplementation for suboptimal gestational thyroid function (SGTF), reported a higher prevalence of elevated attention deficit hyperactivity disorder (ADHD) scores in 9 year-old children exposed to higher thyroid hormone (TH) in utero. Here we investigated if this was accompanied by altered neurodevelopment.Methods: 85 children aged 11-1...

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ea0094p127 | Thyroid | SFEBES2023

Effects of in utero thyroid hormone exposure on adolescent myelination: Quantitative magnetization transfer imaging in the controlled antenatal thyroid screening study

Scholz Anna , McNabb Carolyn , Bloomfield Laura , Bhargava Raghav , Taylor Peter , Lazarus John , Ludgate Marian , Jones Derek , Rees Aled

Introduction: The Controlled Antenatal Thyroid Screening II (CATS) study, a large randomised trial of thyroxine supplementation for suboptimal gestational thyroid function (SGTF), reported higher attention deficit hyperactivity disorder (ADHD) scores in 9 year-old children exposed to higher thyroid hormone (TH) in utero. We investigated if this was accompanied by altered myelination.Methods: Eighty-five children...

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Endocrine Abstracts

Effects of in utero thyroid hormone exposure on human neurodevelopment: MRI analysis from the Controlled Antenatal Thyroid Screening Study

Effects of in utero thyroid hormone exposure on adolescent myelination: Quantitative magnetization transfer imaging in the controlled antenatal thyroid screening study

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